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Differential diagnosis For other causes of 5-oxoprolinuria, beside glutathione synthetase deficiency and 5-oxoprolinase deficiency [9, 29], please see Table 1

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Four RCTs [17, 18, 32, 35] involving 291 patients provided moderate certainty evidence (Table 2) that L-carnitine supplementation has no difference in changes in weight (MD: 0.20, 95%CI: 0.50 to 0.09)

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