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Despite its theoretical appeal for treating insomnia (Xu et al., 2020), the efficacy, optimal dosing, and pharmaceutical formulations of melatonin remain under-researched, indicating a need for further scientific validation to establish its clinical utility (Wieckiewicz et al., 2023)

This method bypasses the digestive system, allowing the body to absorb a higher concentration of vitamins

Jeng, Y.-J., Kochukov, M

Rule out non-spine causes

It was revealed to scavenge hydroxyl radical (OH), superoxide anion radical (O 2 - ), hydrogen peroxide (H 2 O 2 ), hypochlorous acid (HOCl), nitric oxide (NO), peroxynitrite (ONOO - ), singlet oxygen ( 1 O 2 ) and stimulates antioxidant enzymes (AOEs) SOD, Catalase, GPx, GR by nutritional antioxidants (59, 93) ( Figure 3 )