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The transport of inorganic Se into the brain appears to be mainly responsible for Se neurotoxicity (Vinceti et al., 2014, 2016), implementing the U-shaped effects of Se on human health (Rayman et al., 2018

ACS Omega 8(10):93569363 Schwarz M, Lser A, Cheng Q, Wichmann-Costaganna M, Schdel P, Werz O, Arnr ES, Kipp AP (2023) Side-by-side comparison of recombinant human glutathione peroxidases identifies overlapping substrate specificities for soluble hydroperoxides

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"Glutathione Absorption: Mechanisms and Dietary Influences." Journal of Nutritional Biochemistry, 45(3), 112-124