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For example, after 4 weeks of wheel running, the expression of BDNF in the ipsilateral cerebral cortex was significantly increased compared with the control group [88], resulting in increased synaptic plasticity, improved cognitive function and motor function after TBI, reduced TBI-induced damage to the hippocampus, cortex, and thalamus, and decreased neuronal apoptosis, suggesting that exercise preconditioning can increase the secretion of BDNF in brain tissue to exert protective effects on neurons after TBI
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doi: 10.1128/AAC.47.1.170 32 SchirmerR
However, glutathiones relative distribution within cells is difficult to determine because oxidized glutathione (GSSH) rapidly recycles back to reduced glutathione (GSH)
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