Particularly, we found that mean plasma levels of Valine (U:140.9 mol/L, K:127.8 mol/L), Lysine (U:109.9 mol/L, K:95.7 mol/L), Threonine (U:67.5 mol/L, K:57.9 mol/L) and Tryptophan (U:2.9 mol/L, K:2.3 mol/L), fell below the expected ranges for healthy adolescents (UCSF Clinical Core Accepted Reference Ranges) for both those affected with konzo and their unaffected siblings
Cells either received 200 M TBHP alone or co-incubation with NAC, NACET, or diNAC at a range of concentrations, where 200 M had been previously demonstrated to be the maximum concentration to not significantly affect cell viability in ARPE-19 cells [25]
reconstituted refrigerated and used within 30 days
Compact, travel-friendly bottle size supports on-the-go supplementation
Cell Host Microbe 32 , 852862 (2024)