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The considerable recovery of the dopaminergic neuronal clusters in the park flies ensued better negative geotactic behavior in the flies and prolonged their life span, suggesting improvement in motor coordination dysfunction associated with PD

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The roles of PINK1, parkin, and mitochondrial fidelity in Parkinsons disease

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To overcome this challenge, researchers have devised various strategies, for example, inhibitors targeting GSTP1 were developed by incorporating an electrophilic reactive group that interacts with the thiol group of GSH