This aberrant methylation pattern has also been observed in E-cadherin and non-transforming Wnt ligands (Wnt5a, 7a, and 9a), leading to constitutive activation of the Wnt/ -catenin pathway and uncontrolled cellular proliferation (Ying and Tao, 2009)
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Bodega B, Bione S, Dalpr L, Toniolo D, Ornaghi F, Vegetti W, et al