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Berberine and Semaglutide Side Effects Nausea or upset stomach Bloating or constipation Diarrhea or digestive discomfort Dizziness or lightheadedness Fatigue or low energy Headaches Lowered blood pressure Low blood sugar (hypoglycemia) Dehydration from reduced appetite or fluid loss Slower digestion and nutrient absorption Rapid or excessive weight loss Gallbladder issues during quick weight changes How to Take Semaglutide and Berberine for PCOS Start with a lower dose of each and adjust gradually