tirzepatide to retatrutide Comparing the Big 3, Semaglutide, and : r/Mounjaro Retatrutide vs Tirzepatide: Key Differences

Conclusions Evidence accrued so far suggest that GLP-1RA could exert a modest renal benefit alongside CV protection, justifying its place as second-line drug in patients with T2D and CKD not achieving glycemic control with SGLT-2i and metformin according to KDIGO guidelines [87]

Clinical trial eligibility Is the patient potentially eligible for any ongoing retatrutide trials, and would referral to a hepatology or metabolic medicine specialist be appropriate

a 47% greater relative weight loss Average absolute weight lost: 22.8 kg (tirzepatide) vs

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do not dispose of IMP materials in general waste References: NHS guidance on travelling with medicines