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Yes B12 is safe and often necessary during pregnancy

Any Vitamin B12 that is not required by the body is excreted in the urine

NAD-Related Measurements Treated adipocyte systems showed changes including higher intracellular NAD under the experimental conditions

Caution should be exercised in patients with kidney or liver diseases, as well as in those undergoing pharmacological treatments that may interact with the vitamins present in Tiaminal B12. It is essential to assess the need for this treatment in special populations, such as pregnant and lactating women, as well as in the elderly or those with chronic health conditions

Pregnant or nursing mothers on these diets may also need extra B12 support