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[17] When combining these agents , the primary concern is the potential for additive gastrointestinal effects, as both can cause digestive upset
Further, impaired tricarboxylic acid (TCA) cycle and oxidative phosphorylation lead to increased DNA damage and consequently more ROS due to mitochondrial dysfunction
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Sometimes genes can influence the sideeffects an individual experiences when taking a medicine, the MHRA told The Guardian
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