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They degrade through aggregation (clumping), oxidation, and deamidation (loss of amide groups)

In a recent study by our group that examined mortality outcomes from almost 400,000 individuals across the world, we found that CRF was far superior to overweight or obesity status for predicting the risk of death

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Think of it like this: if your car has been running on fumes for months, a quick pit stop for gas wont magically get you across the country