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Interestingly, while PMA and LPS upregulated NOS2 transcription during macrophage polarization, YBX1 and AMPK expression was also remarkably elevated (Supplementary Fig

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L-Carnitine is one of the most extensively characterized cofactors in mitochondrial bioenergetics and serves as a standard reference reagent across multiple research domains

Furthermore, the differences between the agents in terms of the duration of their effect may be due to tachyphylaxis and/or receptor desensitization