Headache Infrequent and usually limited to the initial treatment period
However, research is still limited and further studies are needed.2 3
A meta-analysis of randomized controlled trials found that daily vitamin E supplementation equivalent to 25 to 536 mg/day of RRR --tocopherol for several years resulted in a significant, 10% reduction in the risk of ischemic stroke (five trials, 91,393 participants) and a nonsignificant trend towards an increased risk of hemorrhagic stroke (five trials, 100,748 participants) (120)
Although it is recommended to access intervention as early as possible and it is often said that early intervention is key to positive outcomes for children with autism, this research also found that positive outcomes occurred for children of a wide age range and not just for young children
Currently, the only prescription options include cobalamin delivered intranasally and delivered parenterally (as intramuscular or deep subcutaneous injection).4,7 The intranasal products appear to be well tolerated and are marketed under the brand names, CaloMist and Nascobal
