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It is noteworthy that even fluctuations in ALT levels within the upper limits of the normal reference range may indicate subclinical hepatic dysfunction [48]

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97,98 Benefits of environmental enrichment for dogs include: Reduced stress and anxiety Decreases in stereotypic behaviors (tail chasing, surface licking, pacing, etc.) Increased relaxation Improved cognitive abilities Reduced vocalization (crying/barking) Examples of environmental enrichment include: bonding with owners (petting, grooming), food-based activities (food puzzles, food-stuffed toys), interactive toys and play, investigating new areas, and social interactions with other humans and dogs

Mechanisms involved in the neurotoxicity and abuse liability of nitrous oxide: A narrative review