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The researchers also looked at the risk for antidepressants, which have been tried as an alternative

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Res Exp Med 198:167174 Meister A, Tate SS (1976) Glutathione and related gamma-glutamyl compounds: biosynthesis and utilization

The peptide counteracted picrotoxin (non-competitive GABA receptor Cl channel blocker), isoniazid (inhibitor of glutamic acid decarboxylase and GABA synthesis), and bicuculline (GABA-A antagonist), all through dose-dependent protective effects without producing behavioral changes when administered alone

for instance, lighter skin became apparent after administering high doses for treating other diseases