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In healthy individuals, dosages of up to 5 g per day were shown to be safe and well-tolerated (Salehi et al., 2018)

Y., Qi, Y., Liao, P., Darakhshan, S., Farzaei, M

doi: 10.1007/s00404-015-3692-3 58 MankESenz de PipanMLapillonneACarnielliVPSenterreTShamirRet al

The observation that the insulinotropic actions of GLP-1 are reduced in type 2 diabetes mellitus (T2DM) led to the development of incretin-based therapies GLP-1 receptor agonists and dipeptidyl peptidase 4 (DPP-4) inhibitors for the treatment of hyperglycaemia in these patients

The critical role of physical activity and weight management in knee and hip osteoarthritis: a narrative review