Available at: LinkOpens in New Tab Li H, Toh PZ, Tan JY, Zin MT, Lee CY, Li B, Leolukman M, Bao H, Kang L
Additionally, unlike oral semaglutide, which is a peptide drug, Orforglipron belongs to a category of medications called small-molecule drugs
After we eat, GLP-1 is released from the gut and tells the brain, Youre satiated. It also helps the pancreas release insulin, slows down how quickly food leaves the stomach, and reduces glucagon (a hormone that raises blood sugar)
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However, given high GLP-1 costs and discontinuation rates, success among even a modest proportion of individuals could greatly augment overall efficacy and cost-effectiveness of GLP-1 therapy