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[DOI] [PMC free article] [PubMed] [Google Scholar] 286.Landry M.J., Crimarco A., Perelman D., Durand L.R., Petlura C., Aronica L., Robinson J.L., Kim S.H., Gardner C.D

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Concurrently, Structure Therapeutics is advancing an APJ-targeting molecule into Phase 2 evaluation for obesity, suggesting that the target remains of clinical interest when candidate molecules are appropriately selected

If the migraine improvement were simply a downstream effect of weight loss, you would expect the BMI change to be substantial and to correlate with the degree of migraine improvement