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Examine Relevant Endpoints Did the study measure outcomes that matter physiologically

Mice with increased hepcidin expression showed an increase in total hemoglobin levels and a corresponding increase in red blood cell lifespan, suggesting that hepcidin agonists may help treat abnormal iron absorption in patients with -thalassemia and related diseases

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Together with the electron-impact fragmentation pattern of each identified MCF derivatised 13 C-labelled metabolite, the degree of labelling was estimated based on the variation observed in the fragmentation pattern of 13 C-labelled metabolites in comparison to their counterpart 12 C mass spectrum