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Indeed, E NADP and E NAD are parameters of central importance for cellular metabolism and regulation

But conversely, the very same research also suggested that low levels of B12 contributed to longer sleep duration than normal and posited that it may be because of B12's ability to potentially tackle oxidative stress

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It can promote fatty acid oxidation and reduce hepatic lipogenesis, which may be particularly relevant for patients with obesity, insulin resistance, metabolic dysfunction-associated steatotic liver disease, or type 2 diabetes