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2 At present, APAP overdose is the foremost cause of ALF in the Western world, accounting for nearly 50% of all of the ALF cases in the United States and 60% in the United Kingdom.3, 4 APAP overdose is associated with more than 78,000 emergency department visits, 33,000 hospitalizations, and around 500 deaths each year in the United States.1, 5 Although the majority of APAP overdose cases are intentional (around 70%), cases of therapeutic misadventures are also frequent

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