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Additionally, targeted delivery systems, such as intra-tympanic or nanoparticle-based approaches, could direct the drug specifically to the cochlea or central auditory structures, increasing local efficacy while reducing exposure to other brain regions and peripheral organs

Aspirin-induced asthma: This is an inflammatory response to aspirin or other COX-1 inhibitors

It can lead to fertility problems, hormonal imbalances, and increased risk of developing endometrial cancer