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The incidence is on the order of three to six cases per 10,000 population per year, and prevalence among women is at least 2%

A detailed discussion of the CureGPX4 goal in facilitating the development of new therapies for rare disorders was reviewed recently [25]

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Significant improvements in ALT and AST levels may indicate beneficial effects on underlying hepatic steatosis, while stable or worsening enzymes warrant further investigation to identify alternative causes of liver dysfunction

For type 2 diabetes, GLP-1 receptor agonists are typically long-term therapies, similar to blood pressure or cholesterol medications