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Some people who cannot tolerate tirzepatide GI effects do fine on semaglutide, and vice versa

Importantly, GLP-1 receptor agonists typically cause weight loss, which may be undesirable or even harmful in Parkinson's patients at risk of malnutrition or who are experiencing unintentional weight loss

A small, randomized trial published in The Lancet suggests that those patients treated with a combination of exercise and liraglutide kept weight off better a year after conclusion of the trial compared to those treated with liraglutide alone

Although the study focused on autoimmune patients with diabetes, the findings highlight the potential of GLP-1 receptor agonists in managing cardiovascular risk in the broader autoimmune population

That should be the standard in medicine