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Patients with advanced fibrosis or cirrhosis require specialist hepatology input for surveillance, management of complications, and consideration for emerging therapies or clinical trials

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Recently, HDL have been reported to transport miRNA (Figure 10), which are small non-coding RNAs that suppress gene expression through binding to complimentary target sites in the 3 untranslated region of mRNAs, and thus inhibit translation and induce mRNA degradation (772)

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