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In summary, GLP-1 receptor agonists represent a major advancement in metabolic medicine, with expanding indications and a rapidly evolving evidence base

Abstract Glucagon-like peptide-1 medicines are being prescribed to growing numbers of patients worldwide, for type 2 diabetes, obesity and associated comorbidities, including cardiovascular disease, peripheral artery disease and obstructive sleep apnea, and are revolutionizing public health strategies for these conditions

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They also significantly improved ovarian function and structure in these pigs, as well as modulated hormone levels [115]

Moreover, it is essential to thoroughly investigate both the well-documented and potential species and possibly strains of human gut microbiota that could be used for the production of health-promoting metabolites