IGF-1 LR3: IGFBP-Resistant IGF-1R Agonist Pharmacology IGF-1 LR3 (Long R3 IGF-1, [Arg3]IGF-1 extended with a 13-amino-acid N-terminal extension, 83 total amino acids) is a synthetic analogue of human IGF-1 engineered for two properties: (1) substitution of glutamic acid at position 3 with arginine disrupts the binding site for IGF Binding Proteins (IGFBPs 16), reducing IGFBP affinity approximately 1000-fold compared to native IGF-1
Resveratrol, a polyphenol in grapes and red wine, was shown to reduce body weight gain in high-fat-fed rodents and restore rhythmic oscillation of leptin and insulin, essentially re-synchronizing metabolic hormones that had lost clear rhythms due to diet-induced obesity
The actual injection takes about 10 seconds
Benefits can include: Lower blood pressure Lower total cholesterol Better liver health for those with metabolic dysfunctionassociated steatotic liver disease (MASLD) Lower blood sugar and reduced diabetes risk Lower risk of kidney disease Tirzepatide and orforglipron are newer drugs that dont yet have results from long-term cardiovascular health trials
At Elive Health & Wellness in New Braunfels, TX, peptide therapy is approached with individualized dosing, careful oversight, and ongoing support
