NREM sleep itself is categorized in three stages based on brain wave activity 15,16 : Stage 1 (N1) is when the body is transitioning to sleep
As such, further studies should explore whether the beneficial effects observed in PsO and early PsA could be replicated in other autoimmune disorders, providing broader therapeutic benefits across this category of diseases
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However, genetic variants in GLP-1 receptor (GLP1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) genes influence how strongly an individual's gut responds to these medications, explaining why some tolerate them better than others
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