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Some trials 151 , 152 have demonstrated that metformin use during the first trimester significantly reduced early pregnancy loss, with rates of 10.8% versus 42.2%, 151 and 10% versus 26%, 152 compared with control treatments (e.g., folic acid or no intervention)

149 PengZ.HanC.YuanL.ZhangK.HuangH.RenC

Les dosages varient selon les laboratoires et pour dfinir la prise optimale il convient de se reporter aux conseils dutilisation disponibles pour chaque produit