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BPC-157 may also upregulate the expression of early growth response gene-1 (EGR-1), which is a growth factor with potential benefits for the nervous system, having been suggested to aid in early extracellular matrix (collagen) formation [5]

Some treatment methods are effective because they induce mitochondrial quality control while interfering with the tumor microenvironment-promoting factors

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The combination of inosine with anti-CTLA4 and anti-PD1 antibodies significantly reduced tumor growth in B16-GMCSF mouse models [81]