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Peter Lurie, a former FDA official who now directs the Center for Science in the Public Interest, described allowing peptides to market without clinical testing as a "profound threat" to the FDA's decades-long drug vetting system

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Several basic molecular and cellular mechanisms are shared among brain diseases, such as neuroinflammation, oxidative stress, excitotoxicity, neurodegeneration, disorders of neurogenesis, dysfunction of neurotrophic factor systems, which are most prominent in specific brain structures associated with different brain diseases [104, 105]