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Retatrutide, a next-generation weight loss drug, targets hormones that regulate appetite and fat utilization

Ghrelin attaches to its receptor and prompts the secretion of GH

It recognizes the toxic state and mounts chemicals to clean up this debris

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[48] Analysis results of racemic ethyl 4-chloro-3-hydroxybutyrate are as follows: [49] 1 H-NMR (CDCl 3 ) = 1.28 (3H,t), 2.62 (2H,d), 3.53 (lH,br), [50] 3.60 (2H,d), 4.20 (2H,q), 4.33 (lH,m) [51] [52] Example 3: Preparation of ethyl (RV4-chloro-3-hvdroxybutyrate (4) [53] 40 g (10% w/v) of racemic ethyl 4-chloro-3-hydroxybutyrate was added to a flask containing 360 mL of 0.1M potassium phosphate buffer (pH 8.0) to which 4 g (1% w/ v) of immobilized lipase Novozyme 435 was then added, followed by reacting at 30 0 C