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In some embodiments, the otic formulation or composition comprises about 18% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

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In April 2026, The Foundation for Prader-Willi Research (FPWR) announced a venture philanthropy investment in ConSynance Therapeutics to support the advancement of CSTI-500, ConSynance s investigational therapy for the treatment of behavioral dysregulation and hyperphagia in PWS

doi: 10.1002/14651858.CD011031.pub3 13 BonavinaGTaylorHS