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Nanoformulated codelivery of quercetin and alantolactone promotes an antitumor response through synergistic immunogenic cell death for microsatellite-stable colorectal cancer

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In this complex, the lipid kinase, VPS34 phosphorylates phosphatidylinositol into phosphatidylinositol 3-phosphate, which acts as a recruitment signal for multiple proteins that are necessary for the nucleation of phagophore (Karaka and Gzaik, 2014