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After a recent tirzepatide dose escalation, the patient developed severe vomiting, metabolic derangements, sepsis physiology, and later GI bleeding, requiring coordinated management by endocrinology, gastroenterology, and cardiology.As GLP-1 use expands, careful dose titration, awareness of overlapping syndromes, and early multidisciplinary involvement are essential

The relationship may be causal

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These symptoms do not always mean a serious complication, but they should be assessed quickly

Texas patients receive a physician decision within 2448 hours of submitting their health assessment