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Middle panel: n = 4, p = 0.0101 (RSL3)

The theoretical cancer risk from telomerase activation is the main long-term concern

doi: 10.1073/pnas.1821323116 12 ZhangWTrachoothamDLiuJChenGPelicanoHGarcia-PrietoCet al

Diabetes Care 27(11):26282635 Carr RD, Larsen MO, Jelic K, Lindgren O, Vikman J, Holst JJ et al (2010) Secretion and dipeptidyl peptidase-4-mediated metabolism of incretin hormones after a mixed meal or glucose ingestion in obese compared to lean, nondiabetic men

Mood and Sleep Disorders The proportion of adult patients in 1-year controlled trials of QSYMIA reporting one or more adverse reactions related to mood and sleep disorders was 15% and 21% with QSYMIA 7.5 mg/46 mg and 15 mg/92 mg, respectively, compared to 10% with placebo