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a PDE-5 inhibitor such as sildenafil PT-141 is administered prior to administration of PT-141 , preferably between about 5 minutes and 45 minutes prior to administration of PT-141, more preferably between about 10 and 30 minutes prior, and more preferably still, between about 15 and 20 minutes prior to administration of PT-141

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Interestingly, the same group could demonstrate that treatment with Liraglutide at 10nM enhanced the migration capacity of hBMSC, suggesting context-specific effects of the drug beyond its influence on proliferation [21]

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No effect of either intervention was observed for lipid profiles, insulin sensitivity, or glucose tolerance