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Clinical trial data referenced in this overview involves FDA-approved formulations under controlled research conditions

The findings support the use of once-weekly subcutaneous semaglutide at a dose of 2.4 mg for weight management and treatment of pain in persons with obesity and moderate to severe pain due to knee osteoarthritis.

For instance, some employers choose to exclude GLP-1 drugs from employer-sponsored health plans, some insurance plans require prior authorization before approval, and Medicare does not cover GLP-1s for weight loss

Serious risks are rare but possible in immunocompromised individuals or those with severe underlying health conditions