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In more extreme cases, it can cause significant nutritional deficiencies and a reduction in body weight as it struggles to absorb and process nutrients efficiently

Second, due to the open-label design, both the investigators and participants were aware of the treatment allocation, which could systematically influence the evaluation of therapeutic efficacy

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It notes head-to-head comparison data is limited and argues real-world adherence often favors the oral route, since people with injection anxiety may stay on treatment longer with a tablet