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Phase 2 trial data (Jastreboff et al., NEJM, 2023) showed mean body weight reductions of approximately 24% at 48 weeks with the highest dose, with no clear plateau observed

Instead, they change several biological systems that influence eating behavior and energy intake

The marginal cost of producing a little more of medications is very small. The pharmaceutical industry, they hem and haw about how they wont make money, and they have made, like, a trillion dollars on these products, Nunn continued

Most talked about is the need to minimise muscle loss through higher protein intake

If your insurance excludes obesity medications entirely, manufacturer programs wont help