According to a study published in Diabetes, Obesity and Metabolism that assessed the occurrence of gastrointestinal (GI) adverse events (AEs) with a 2.4-milligram weekly dose, 29.7% of participants reported diarrhea and 24.2% had constipation
The results are slightly lower but still clinically significant for most patients
B12 is an essential water-soluble vitamin, also known as cobalamin, responsible for critical functions like red blood cell formation, brain health, and DNA synthesis
Clinical trials have specifically looked at men with this condition who also have symptoms of testosterone deficiency
However, people taking these medicines must be watched closely because of uncommon, but serious adverse reactions: Infections from bacteria, viruses, and fungi Skin cancer, but not melanoma Skin reactions Allergic reactions Worsened heart failure Damage to nerves Low white blood cell count SURGERY Surgery may be needed to correct severely damaged joints