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As a modified fragment of human growth hormone, it provides a model system for studying how specific peptide domains influence receptor interaction and downstream signaling

The coding sequences of genes obtained in the genetic screen were amplified from the pFL44L plasmids extracted from the library and subcloned into pRS426- TEF (2 ) plasmids using primers listed in Supplementary Table 2, which introduced Sma I and Xho I restriction sites

96 The RAF-MEK-ERK pathway can be activated by various stimuli, for example PMA and Fc receptors (FcRIIIb), to induce NETosis

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The HPA axis mediates the body stress response, and dysregulation of this axis can amplify immune activation