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Another study found that methylation-mediated downregulation of miR-200c is associated with increased invasive potential in NSCLC cell lines [85]

Various subcortical networks communicate with the mPFC, including the amygdala (responsible for emotional processing), the NAc (responsible for social incentive), and the hypothalamus (responsible for stress regulation)

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Tapering may be helpful if using long term (6+ weeks), but isnt physiologically necessary