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However, this is a minor factor compared to temperature, light, and solvent choice

This method bypasses the digestive system, making it ideal for people who: Have trouble absorbing B12 due to gastrointestinal issues (like Crohns disease or coeliac disease) Are on medications that interfere with B12 absorption (like metformin or anti-acids) Follow vegan or vegetarian diets Have undergone gastric surgery

Five mechanistic axes are documented: 1

Present as an array of non-depressive mood disorders, including agitation, confusion, and amnesia [10]