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Contraindications for phentermine include uncontrolled hypertension, coronary artery disease, and certain arrhythmias

Zepbound, for example, is FDA-approved for adults with obesity or overweight with at least one weight-related condition, in addition to nutrition and activity changes

Some researchers address retatrutide plateaus by temporarily increasing the dose for 2-4 weeks before returning to their maintenance dose

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GLP-1 medications can generally be restarted after a break, though you will typically need to re-titrate from a lower dose to allow your body to readjust and minimize side effects