423 These findings further confirmed the central role of the CNS in regulating the anti-inflammatory effects of GLP-1RAs, highlighting the potential application of GLP-1RAs in anti-inflammatory treatment
Zhu Z, Zhang F, Hu H, Bakshi A, Robinson MR, Powell JE, et al
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GLP-1 exerts its anorectic effect in part by acting on the hunger-satiety centre located in the arcuate nucleus of the hypothalamus, and in part by delaying gastric emptying
In a 72-week clinical trial, those patients who took the highest dose of Zepbound (15 mg) had, on average, a weight reduction of 20.99%