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Signs of Vitamin B12 Deficiency Some common signs that you may be deficient in Vitamin B12 include fatigue or tiredness, weakness, difficulty concentrating or thinking clearly, pale skin, dizziness or light-headedness, loss of appetite, weight loss, constipation or diarrhea, numbness or tingling in the hands and feet, sore tongue, headaches and vision problems
Methylmalonic acid is a sensitive biomarker used to diagnose vitamin B12 deficiency, especially in borderline cases
B 12r appears orange-brown in solution, while B 12s appears bluish-green under natural daylight, and purple under artificial light