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albicans via receptors such as -glucan recognizing receptors (e.g., Dectin-1) and in response, release a variety of mediators including tryptase, histamine, prostaglandins (PGs), leukotrienes (LTs), and various cytokines, mainly CCL3, CCL4, TNF-, IL-6, and IL-10 [65, 85] (Fig

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When to Refer a Patient We accept referrals for patients who meet the following criteria: 2 weeks or more post-surgery Have completed their initial surgeon follow-up Have fully healed and closed incisions Starting or preparing to start physical therapy Have expected post-op stiffness, inflammation, or early pain Want to optimize healing during the critical first 12 weeks of tissue remodeling If youre unsure whether a patient is a candidate, we welcome your call