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In addition to cytochrome c , other IMS proteins are also mobilized and released into the cytosol where they promote or counteract caspase activation and hence cell death (Li et al., 2001

There are several pathways via which nutrients can influence neuroinflammation: a more direct impact, with nutrient-derived messengers crossing the BBB and thereby exerting their effects directly in the CNS or a more indirect pathway, with nutrients modulating peripheral inflammation, that can in turn exert its effect on the central immune system